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First at TPM … In important development overnight, the Trump administration is now openly colluding with Texas Gov. Greg Abbott...

Scientists have created a highly efficient catalyst that breaks down stubborn lignin from plant waste into useful chemicals under relatively mild conditions. By revealing exactly how the catalyst works at the atomic level, the discovery could help turn forestry and agricultural waste into renewable building blocks for fuels, plastics, and other materials.

Researchers have found a way to supercharge natural killer cells, powerful immune cells that can attack cancer, so they can penetrate solid tumors and keep fighting once inside. In mice, these specially prepared tissue-resident cells slowed the growth of several tumors, including melanoma and head and neck cancers, and worked even better when paired with the antibody drug cetuximab.

A sweeping analysis of thousands of animal genomes suggests that chromosomes do not evolve randomly but instead follow a limited number of irreversible “evolutionary highways.” These one-way genetic changes preserve clues to more than 600 million years of animal history and could even help researchers explore where evolution may head next.

A huge section of Greenland’s Petermann Glacier has snapped off, forming an ice island about the size of Manhattan. Satellites watched cracks spread rapidly before the 76-square-kilometer slab finally broke free on August 4. It is the glacier’s biggest calving event since 2012, and scientists say two even larger pieces could eventually follow. The rare Arctic iceberg will now be tracked as it drifts, breaks apart, and potentially affects shipping routes.

NASA scientists found that microbes brought by astronauts could survive in cold, shadowed niches around the Moon’s South Pole, potentially complicating future searches for pristine lunar chemistry. Some refuges may be no larger than a footprint, while one hardy fungus could even withstand limited exposure to sunlight.

A major study found that adults with depression show disrupted production of new neurons in the hippocampus, potentially weakening the brain’s ability to separate new experiences from painful memories. The researchers also identified broad molecular changes that could open the door to new treatments tailored to different biological forms of depression.

A massive test of gravity across the cosmos found that it behaves almost exactly as Newton and Einstein predicted, even across galaxy clusters hundreds of millions of light-years apart. The result weakens some modified-gravity explanations and strengthens the case that dark matter is behind the universe’s mysterious missing mass.

Older adults who received the Shingrix shingles vaccine were 24% less likely to be diagnosed with dementia over four years in a study of more than 500,000 people. Researchers estimate the difference could amount to roughly one dementia case prevented for every 17 people vaccinated.

People who reach 110 and beyond appear to have unusually large numbers of rare immune cells capable of killing abnormal cells. These CD4 cytotoxic T cells became more common with age and often expanded into large groups of nearly identical cells, suggesting the immune system was repeatedly responding to persistent threats.

Tesla raised the price of the Cybertruck by $5,000 on Monday night, quietly updating its online configurator without changing a single spec.

The Dual Motor all-wheel drive now starts at $74,990, up from $69,990. And it comes while Tesla is running the Cybertruck line at roughly 10% of its planned capacity.

Folks have been daisy-chaining Macs for AI—this refresh keeps that in mind.

“U.S. debt hasn’t been further downgraded, breakeven rates on inflation-protected bonds haven’t spiked, and the cost of insuring against a federal default hasn’t skyrocketed, signs that most investors still see U.S. bonds as a largely risk-free bet even if they have been ​demanding higher interest rates,” Reuters reports. “That’s the good news.” “Not so great […]

House Minority Leader Hakeem Jeffries (D-NY) said that “no one from the Trump Cartel is getting a pass,” The Hill reports. The statement comes after he faced backlash for meeting with Jared Kushner, President Trump’s son-in-law. Said Jeffries: “I shouldn’t have to say it, but I am. No one is going to get a pass. […]

Plus, what Justice Thomas said on Sen. Ted Cruz’s podcast.

Apple Newsroom: Apple today debuted M6 in the new Mac mini and M5 Ultra in the new Mac Studio, providing an extraordinary leap in performance and AI capabilities. M6, Apple’s first state-of-the-art 2-nanometer chip, advances every compute block, delivering gains across e...

America’s best chance of competing with China isn’t Detroit — it’s Silicon Valley, on the self-driving tech already being tested on San Francisco streets.

As a trip to Australia approaches, the team is trying to outrun an onslaught of self-inflicted distractions.

Tony Vitello‘s club is a skeleton of its Opening Day self as just seven players on Monday’s roster were around when the season began.

Years of delays, a pandemic, and some neighborhood drama couldn't stop the 73-year-old Cinderella Bakery from bringing its honey cake and piroshki to 24th Street.