An experimental compound called AP503 significantly strengthened bones in mice by activating GPR133, a receptor that boosts bone formation while slowing bone loss. Because the same treatment has also been linked to stronger muscles, researchers see intriguing potential for combating age-related decline and osteoporosis.

Interstellar comet 3I/ATLAS contains exceptionally high levels of methanol, suggesting it formed under conditions very different from those that shaped most comets in our solar system. ALMA also revealed that tiny icy grains around the comet are releasing methanol like miniature comets, giving astronomers an unusually detailed look at an object from another star system.

Two major alien-life announcements in 2025 generated enormous excitement, but most astrobiologists remained unconvinced. Only 6.6% of surveyed experts thought possible biological molecules on K2-18b probably represented extraterrestrial life, while 15.1% said the same about intriguing mineral patterns in a Martian rock.

Semaglutide, the drug found in Ozempic and Wegovy, was linked to nearly 40% fewer asthma attacks in a large real-world study. It was also associated with about 20% fewer COPD flare-ups. Researchers say GLP-1 drugs may offer respiratory benefits in addition to their effects on diabetes and obesity, but clinical trials are needed to confirm the findings.

Britain’s towering Devil’s Arrows were built from 25-tonne stones hauled at least 18 kilometers from Brimham Rocks around 4,000 years ago. The discovery reveals an astonishing feat of prehistoric engineering and suggests the stones’ distant source may have been chosen for cultural or spiritual reasons.

Scientists found that a tiny atomic structure that forms on nickel oxide during methane conversion is more effective than the metallic nickel long believed to drive the reaction. The discovery allowed a low-nickel catalyst to rival one containing 10 times more metal, potentially opening the door to cheaper and more efficient industrial catalysts.

Insects quietly hold much of the natural world together, yet conservation efforts are overlooking the tropical regions where more than 80 percent of insect species live. Monash University researchers have developed a global framework to close this gap by combining scientific studies with museum collections, local expertise, citizen science, social media records, and new technologies.

Scientists found that caffeine activates an ancient cellular energy system involved in stress resistance, DNA repair, and growth. The discovery could help explain caffeine’s links to healthier aging and may point toward new ways to target the same pathway.

Volcanic rocks in Colombia are rewriting the timeline of the collision between Central and South America. Their magnetic signatures show that major tectonic deformation had already weakened by the late Miocene, suggesting the most intense collision occurred earlier than previously believed.

A new analysis of more than 1,700 supernovae is questioning whether the universe is really accelerating at all. After accounting for the ages of the stars that produce these explosions, researchers found signs that cosmic expansion may actually be slowing. They also argue that the apparent acceleration changes with direction, which would be difficult to explain with dark energy. Other cosmologists dispute the conclusion, setting up a major test for upcoming observatories.

Astronomers have detected an exceptionally faint hydrogen radio signal from billions of light-years away using South Africa’s MeerKAT telescope. Instead of finding galaxies one at a time, the technique measures their combined hydrogen glow across enormous stretches of space. The successful detection shows that astronomers may soon be able to create much larger 3D maps of the Universe.

Researchers discovered that combinations of toxin-blocking proteins naturally found in rattlesnake blood can powerfully neutralize venom from several dangerous snake species. In lab tests, the mixtures were about 10 times more potent than a current commercial antivenom, pointing toward a new generation of nature-inspired snakebite treatments.

Scientists have identified a giant new dinosaur from Brazil that reached about 20 meters long and lived 120 million years ago. Its surprising evolutionary ties to a Spanish dinosaur suggest its ancestors crossed ancient land connections between Europe, Africa, and South America.

Semaglutide, the drug behind Ozempic and Wegovy, may have benefits that extend well beyond weight loss and diabetes. In a large Swedish study of nearly 15,000 people with bipolar disorder, its use was linked to a 21% lower risk of psychiatric hospitalization. Researchers think effects on inflammation and brain-related biological pathways could help stabilize mood, though other GLP-1 drugs did not show the same association.

The extinct “American cheetah” was not really a cheetah at all, but a puma relative with an unexpectedly flexible lifestyle. Fossils from the Yukon suggest northern populations survived partly by eating fish, possibly including salmon, while southern cats hunted on land.

More than 1,200 genetic variants have been linked to the Big Five personality traits, and many of the same variants are also associated with health, longevity, careers, income, and everyday habits. The findings reveal a surprisingly wide genetic connection between personality and life outcomes while showing that environment still plays a powerful role.

Physicists have directly observed a long-predicted quantum effect of gravity, putting one of Einstein’s foundational ideas to a striking new test. Using ultracold atoms, researchers split an atom’s quantum wave so that one part was held in place while the other fell freely under gravity, then reunited the two to measure the tiny difference that emerged.

A chemical commonly used in dry cleaning and found in some household products may be an overlooked threat to liver health. Researchers found that people with detectable levels of tetrachloroethylene (PCE) in their blood were three times more likely to have significant liver fibrosis, a dangerous buildup of scar tissue that can eventually lead to liver failure or cancer. The risk climbed sharply as PCE levels increased, even after accounting for factors such as age, sex, race, education, alcohol use, and metabolic conditions.

A critically endangered roloway monkey has given birth just months after surgeons performed an unusual operation that saved her foot from amputation. Her new daughter, Lagertha, is an important addition to a species believed to number fewer than 2,000 in the wild.

Cancer is becoming an even larger global health threat, with nearly 21 million people diagnosed and 9.8 million dying from the disease in 2024. New estimates suggest about 1 in 5 people worldwide will develop cancer during their lifetime, while cases could climb by 67% to 34 million by 2050 simply because populations are growing and aging.

Could math help explain why some relationships survive life’s inevitable stresses while others slowly fall apart? Researchers have spent decades developing mathematical models that treat romantic feelings as changing systems, revealing patterns in attraction, emotional reactions, conflict, and recovery.

A rediscovered memoir reveals that celebrated War of 1812 veteran Shadrack Byfield was far more rebellious and troubled than history has portrayed, battling chronic pain, poverty, authorities, and even rivals at his local chapel. The soldier who buried his own amputated arm and invented a custom prosthesis spent decades fiercely fighting for the pension and independence he believed he had earned.

A surprising immune system signal may help explain why zebrafish can regenerate damaged spinal cords so effectively. Researchers found that certain neutrophils release Il-4, which calms harmful inflammation and allows injured nerve fibers to grow again. Without these cells, healing stalled, but adding Il-4 restored regeneration. Scientists now want to know whether the same mechanism could someday be harnessed to improve spinal cord repair in humans.

A large study of nearly 74,000 men suggests that long-term use of tadalafil, best known as Cialis, may be linked to a higher risk of glaucoma and other eye pressure problems. Men prescribed the drug for urinary symptoms caused by an enlarged prostate were 22% more likely to develop glaucoma, 32% more likely to develop ocular hypertension, and 33% more likely to be diagnosed with primary open-angle glaucoma or start glaucoma treatment over five years.

Scientists have devised a new way to switch magnetic computer memory while using far less energy than today's leading technologies. By mathematically optimizing the pulses used to flip digital bits, the method could reduce energy consumption by several orders of magnitude. Simulations suggest it may bring future memory devices surprisingly close to the fundamental physical limit for processing information. The same idea could eventually work with electrical currents or ultrafast lasers.

Scientists have found evidence that some gut bacterial populations can spread rapidly between people and across continents, suggesting the microbiome may be more transmissible than previously thought. The research also revealed hidden bacterial groups associated with aging, colorectal cancer, inflammatory bowel disease, and type 2 diabetes.

East Antarctica gained an astonishing 695 billion tons of ice between 2021 and 2023, temporarily slowing Antarctica’s long-term decline. Researchers found that warming thousands of miles away in the tropical ocean altered atmospheric circulation and funneled moisture toward the continent, triggering exceptionally heavy snowfall.

Researchers have found a potential way to attack prostate cancers that evade treatment by changing their cellular identity. Combining two types of drugs reversed many of these changes and sharply slowed tumor growth in preclinical experiments, offering a possible new strategy for aggressive, treatment-resistant disease.

MIT engineers have developed injectable “mini livers” designed to help support people whose failing livers can no longer perform essential jobs. Instead of replacing the damaged organ, the approach injects liver cells together with tiny hydrogel spheres and supportive cells, creating a pocket of functioning tissue that can connect to the bloodstream.

A more realistic quantum model has revealed evidence that strange, nearly immobile quasiparticles called fractons could exist in solid materials. Their inability to move freely could make them promising building blocks for unusually robust quantum information storage.