A low-fat vegan diet may help people lose weight without counting calories, shrinking portions, or feeling constantly hungry. In a 16-week clinical trial, people eating mostly fruits, vegetables, grains, and legumes consumed about 357 fewer calories per day even though the total amount of food they ate barely changed.

Scientists are searching some of Earth’s oldest rocks for tiny fossils that could reveal how simple microbial life made the extraordinary leap toward plants, animals, and other complex organisms. Solving that ancient mystery may also help determine whether complex life could emerge on worlds beyond Earth.

Astronomers may finally have a clue to what happens to the mysterious “little red dots” that crowded the early universe. By studying a spiral galaxy nicknamed the “Saguaro,” researchers found a compact, bright red center that closely resembles these distant objects—but with something Webb usually can’t see around them: a full galaxy. When the team simulated what the Saguaro would look like much farther away, its spiral structure essentially vanished, leaving only the bright red core.

Caltech scientists have created ultra-low-loss optical pathways on silicon chips that approach the efficiency of fiber optics and dramatically outperform existing technology at visible wavelengths. The breakthrough could unlock more powerful lasers, miniature atomic sensors and clocks, quantum systems, and more energy-efficient data centers.

Researchers have uncovered a surprising way triple-negative breast cancer may turn the body against itself. Tumors appear to recruit macrophages—immune cells normally involved in healing and fighting infection—and use them to release a protein called BDNF that draws nerves into the tumor. Those nerves may then help the cancer grow, resist treatment, and potentially spread.

Researchers combined synthetic DNA with a semiconductor to create an ultra-low-power memory device capable of storing and processing information in the same place. The bio-hybrid technology could eventually help make AI systems and next-generation computers far more energy efficient.

An eight-year Finnish study found that children who spent more time on screens tended to show better cognitive processing as teenagers, challenging common assumptions about screen use. Researchers say the key may be balancing physical activity with screen activities that encourage learning, creativity, and active thinking.

Scientists have discovered that tiny, sharply curved wrinkles in graphene can dramatically alter its electrical behavior, creating surprisingly strong charge separation. The finding suggests future electronics could be tuned by reshaping materials at the atomic scale instead of changing what they’re made of.

Nature invented biodegradable plastic long before humans did—and animals may have been feeding on it for hundreds of millions of years. Researchers discovered that dozens of animal species possess enzymes capable of breaking down microbial bioplastics called PHAs, a talent once thought to belong only to microorganisms.

An experimental Alzheimer’s compound prevented damaging protein clumps from forming in the brains of mice, helping nerve cells survive longer and reducing amyloid buildup. The treatment also appeared to improve heart health and slow some signs of aging, raising hopes for an entirely new way to combat dementia.

As we age, the body appears to sacrifice walking efficiency in exchange for stability. Older adults stiffen the ankle more with each step, which may help prevent falls but also forces the muscles to work harder while producing less forward motion. This leads to shorter strides, slower walking, and faster fatigue. Exercises targeting balance, coordination, and lower-leg strength could help preserve mobility.

Physicists may have uncovered a hidden feature inside protons that helps preserve one of matter’s most fundamental properties. RHIC collision data suggest baryon number is carried not simply by three quarks, but by a Y-shaped junction of the gluons connecting them. The finding challenges a decades-old textbook picture and could deepen our understanding of why protons—and ultimately matter itself—remain stable.

A centuries-old heart drug costing less than ten cents a day could help keep heart-failure patients out of the hospital. New research suggests low-dose digoxin can reduce heart-failure hospitalizations by about 25%, potentially paving the way for its return as a major treatment.

Aging gradually wears down the cartilage and fluid that protect our joints, but avoiding movement may actually make matters worse. Exercise helps nourish cartilage, strengthens the muscles that protect joints, and can reduce osteoarthritis pain. Low-impact activities such as swimming, cycling, tai chi, yoga, and walking on varied terrain may also improve balance and mobility. Even a few minutes of the right kind of movement can make a difference.

Astronomers have witnessed a black hole violently shredding a massive star, creating one of the most energetic stellar explosions ever observed. The event, nicknamed “the Whippet,” briefly released about 400 billion times the Sun’s energy and sent a shock wave racing outward at one-fifth the speed of light. Months later, scientists spotted unexpectedly fast-moving helium, suggesting that some structure may have survived the destruction.

Exercise and healthy blood sugar levels in midlife may help slow cognitive decline decades later. Physical activity appeared especially beneficial for Mexican American adults, suggesting that some brain-protective factors may differ across populations.

Scientists have discovered a new extinct amphibian species hiding in the fossil collections of Los Angeles’ La Brea Tar Pits. Named Spea labreae, the Ice Age spadefoot toad is an exceptionally rare find—only one other extinct Pleistocene amphibian has ever been identified in North America. Its bones had been sitting in collections since the 1950s before a researcher noticed features that set it apart from known species.

COVID-19 can reactivate dormant viruses hiding in the body, including Epstein-Barr, cytomegalovirus, and several herpes viruses. One poorly understood viral family was strongly associated with long COVID and lasting disability, offering a potentially important clue to why some patients struggle to recover.

Rising carbon dioxide in the atmosphere may be leaving a measurable imprint inside the human body. Researchers analyzing more than two decades of U.S. health data found that blood bicarbonate levels have climbed about 7% since 1999, while calcium and phosphorus have declined—changes that closely track increasing atmospheric CO2.

Gut microbes need something to eat, and when fiber is limited, they may begin consuming proteins from the mucus lining that protects the gut. Researchers found that fiber can suppress this process, while indigestible plant proteins help microbes produce more beneficial compounds.

A widely available food-preservation chemical is emerging as a disturbing factor in rising UK suicide deaths, particularly among younger people and men. Researchers say the scale may be underestimated and are calling for urgent restrictions on access and harmful online information.

Fossils collected in Osaka more than 30 years ago have revealed a surprise hiding in plain sight: four previously unrecognized bones from a giant Cretaceous mosasaur. Among them is the first confirmed premaxilla—the frontmost bone of the upper jaw—ever identified in a Japanese mosasaur fossil. Even more intriguing, parts of the skull show unusual anatomical features that don’t match known mosasaurs, raising the possibility that the remains belong to an entirely new species.

Scientists have long thought an unusual genetic system helped ants, bees, and wasps evolve their extraordinary social colonies. A massive new analysis suggests that genetics alone can’t explain it—and the real secret may lie in other traits unique to these insects.

Scientists have uncovered why two seemingly opposite ways of targeting the same brain receptor can both promote weight loss. In mice, activating the GIP receptor in the brainstem reduced appetite, while blocking it in the hypothalamus removed a kind of “brake” on fullness signals. The discovery helps explain why very different obesity drugs can achieve similar results and suggests that carefully combining GIP-targeting treatments with GLP-1 drugs like those related to Wegovy and Ozempic could produce stronger effects.

A surprising stress-related signal may help the brain repair itself after injury. Researchers found that myelin-producing precursor cells rapidly release the stress hormone CRH near damaged brain tissue, helping control how those cells mature and rebuild protective nerve insulation. The same system also influences brain development and the thickness of myelin later in life. The findings could offer new clues about how early-life stress contributes to psychiatric disorders.

A tiny superconducting engine has successfully converted heat near absolute zero into useful work, demonstrating the first cyclic quantum heat engine of its kind. Future versions could operate autonomously inside quantum computers, potentially eliminating huge numbers of costly, noise-producing microwave cables.

Nuclear reactors may go dark, but their fuel continues producing a faint antineutrino “glow” long after shutdown. Researchers have now detected that residual signal for the first time, finding it closely matched predictions of radioactive decay inside the reactor and nearby spent-fuel pools. The breakthrough suggests antineutrino detectors could eventually monitor reactors even when they are offline.

Scientists have discovered that the aging human brain may be far less isolated from the rest of the body than once believed. Stanford researchers found that large numbers of immune cells from the blood begin entering the brain as early as middle age, where they can transform into microglia, the brain’s specialized immune cells. The finding overturns a long-standing assumption that these cells remain largely separate from the body’s immune system throughout life.

Scientists have found that the AMOC may be far more vulnerable to rapid warming than to temperature alone. When warming happens slowly, the ocean can adapt, but at faster rates similar to today’s, the massive Atlantic circulation could reach a tipping point at much lower temperatures.

Simply choosing the stairs could have surprisingly big benefits for your heart and longevity. A large analysis involving more than 480,000 people found that regular stair climbers were 39% less likely to die from cardiovascular disease and 24% less likely to die from any cause than people who rarely took the stairs. They also had lower risks of heart attack, stroke, and heart failure.