“Mary Brunkow, Fred Ramsdell, and Shimon Sakaguchi won the 2025 Nobel Prize in Physiology or Medicine for work shedding light on how the immune system spares healthy cells, creating openings for possible new autoimmune disease and cancer treatments.”
Jason Kottke's weblog, home of fine hypertext products since 1998
- Public lists
-
Featured
- Fetched
Empty Nest? Or Open Door?
How to Write in Cuneiform, the Oldest Writing System in the World....
In Praise of Comfort Films
Tim Berners-Lee: “I gave the world wide web away for free because...
Oh I don’t know, the appearance of two perfectly overlapping fiery rings...
Oh I don’t know, the appearance of two perfectly overlapping fiery rings in the sky doesn’t seem like a good omen to me, even at low frequencies.
We Are Not Fascists, and If You Call Us Fascists, We Will...
Keeping Up Appearances star Patricia Routledge dies at 96. I loved that...
80 of the Most Iconic Guitar Intros
Watch as Paul Davids plays 80 of rock’s most iconic guitar intros, including ones from Robert Johnson, Chuck Berry, The Kinks, Cream, Jimi Hendrix, Black Sabbath, ZZ Top, Joan Jett, AC/DC, Blur, and The White Stripes.
Name A 28-Year-Old. “The data tells us that 3,880,894 children were born...
I think I’m gonna read Edith Wharton’s The Age of Innocence next,...
I think I’m gonna read Edith Wharton’s The Age of Innocence next, inspired by Evan Puschak’s recent video. Just downloaded the free ebook from Standard Ebooks.
Harvard Library’s collection of Soviet and post-Soviet lapel pins. Sputnik, Aeroflot, the...
Swift Justice: A Look Inside a Taliban Courtroom
Life Is More Than an Engineering Problem, an interview with Ted Chiang...
The 25 Most Influential Magazine Covers of All Time, including, of course,...
Instead of hiding rips and tears, the visible mending movement turns them...
Old Masters, New Media
When Kittens Came to My Prison, I Had Not Petted One in...
A Chronology of All 113 Prints of Hokusai’s The Great Wave
Are you ok? In a recent video, Hank Green tells his brother...
Are you ok? In a recent video, Hank Green tells his brother John: I’ve Not Been Doing Well. Lots of what Green says here resonates with me.
Quentin Blake: How I Draw

Illustrator Quentin Blake, who is most widely known for his energetic drawings for Roald Dahl’s books, generously shares his drawing process on his website and also in a series of videos.
I do a freewheeling sort of drawing that looks as though it is done on the spur of the moment. However even a single drawing needs a certain amount of preparation and planning. Most of the time I need to do a rough in which I find out how people stand, what sort of expressions they have and how they fit on the page.
Here are some of the videos he’s done. Quentin Blake draws a Hornswoggler:
Ten Minutes of Illustration (in three parts for some reason):
The illustration above is from The Wild Washerwomen.
Tags: art · books · how to · illustration · Quentin Blake
The official number of exoplanets tracked by NASA has reached 6000. Astronomers...
Musician Plays the Last Stradivarius Guitar in the World, the “Sabionari” Made...
A company called Blackdot has built a tattooing robot. The company says...
A company called Blackdot has built a tattooing robot. The company says the machine is less painful and the tattoos look like they are laser-printed.
Have I Earned It?
Craig Mod is off on another of his long walks of Japan and is writing a pop-up newsletter (subscribe!) along the way. I am feeling this bit from his first missive recently:
To have a day like today feels a bit selfish, even more so after having met Vlad. He wonders, always wonders, if he has earned it. The time alone, the steps, the little interactions, the looking closely at the world. He takes it, he’ll take whatever he can get whenever, and try to be as grateful as possible. What else is there? Tiny men with big sticks upend sanity the world ‘round and all you can do is try to find your footing and push back.
Tags: Craig Mod
A new kind of bone glue that “mimics how oysters stick to...
A new kind of bone glue that “mimics how oysters stick to underwater surfaces” can bond bone fragments together in 2-3 minutes, “even in blood-rich areas where most adhesives fail”.
25 years ago today, Radiohead released Kid A. This morning, I’m celebrating...
“Scientists reflect on the life and work of [Jane Goodall], whose discoveries...
“Scientists reflect on the life and work of [Jane Goodall], whose discoveries made them rethink what it means to be human.”
Amateurs! How We Built Internet Culture and Why it Matters. “A bold,...
Every Click
Korean artist group Shinseungback Kimyonghun made a video of every time they clicked their mouse. It’s mesmerizing.
[This is a vintage post originally from Jan 2014.]
Tags: mesmerizing · Shinseungback Kimyonghun · timeless posts · video