Oxygen is disappearing from oceans, lakes, rivers, and coastal waters at an alarming rate, threatening aquatic life and weakening the natural processes that help regulate Earth’s climate. Scientists warn that this widespread deoxygenation is closely connected to other major planetary threats, including warming, pollution, biodiversity loss, and ocean acidification.

Researchers have uncovered a surprising culprit behind sleep loss in Alzheimer’s disease: the brain’s own immune cells. In mice with amyloid plaques, overactive microglia triggered inflammation that kept the brain from getting enough deep, restorative sleep. Temporarily removing most of these cells restored more than two hours of sleep per day, even though the plaques remained unchanged.

Scientists have redesigned zinc oxide particles to create a mineral sunscreen that protects against ultraviolet radiation without leaving such a noticeable white cast. The SPF 30 formula could make sunscreen easier and more appealing to use across a wider range of skin tones.

Scientists are testing two promising ways to destroy PFAS, the stubborn “forever chemicals” that can accumulate in water and resist normal treatment. One method uses collapsing vapor bubbles to generate extreme heat and reactive molecules, while the other uses cold plasma and rising gas bubbles to pull PFAS to the surface and break them apart.

A protein called SORLA may act as a powerful defense against the toxic tau tangles involved in Alzheimer’s disease. Mice with extra SORLA had less tau accumulation, less brain atrophy, and healthier connections between neurons, while mice without it experienced more severe damage. The findings also revealed a possible drug target that could help control harmful activity in supporting brain cells.

Scientists have discovered a hidden warning sign of skin damage that appears before collagen fibers visibly thin, break, or lose their connections. Using advanced light-based techniques, the team found that collagen’s carefully organized molecular “handedness” can collapse even while the tissue still appears structurally intact and contains the same amount of collagen. This suggests that skin may begin deteriorating at a much deeper level long before conventional imaging can detect a problem.

The mysterious sound known as The Hum has been reported worldwide for decades, yet its source often remains impossible to find. Researchers tested whether people who hear it have exceptional low-frequency hearing or measurable sounds produced inside their ears, but neither explanation fit most participants. The strongest possibility is that many cases involve low-frequency tinnitus, even though the sound seems completely external.

Researchers have created cosmic dust from scratch by recreating space-like conditions inside glass tubes. The dust contains complex carbon-rich molecules built from elements essential to life and produces infrared signals similar to real material found in space. By studying these laboratory samples, scientists can explore how organic chemistry unfolds around stars and how comets, asteroids and meteorites may have carried those ingredients to Earth.

A new AI-powered blood test could give people a remarkably early warning of serious heart and circulation problems. Developed by researchers at the University of Hong Kong, CardiOmicScore analyzes thousands of proteins and metabolites to estimate the risk of six major cardiovascular diseases, including heart attack, stroke, heart failure, and atrial fibrillation. Unlike genetic risk scores, which remain fixed throughout life, the system captures biological changes linked to a person’s current health, lifestyle, and environment.

Scientists may have uncovered one reason coffee is repeatedly associated with healthier aging and lower disease risk. Compounds in coffee appear to activate NR4A1, a receptor that helps protect cells from stress, inflammation, and damage. These protective effects disappeared when the receptor was removed, strengthening the connection. Surprisingly, plant-based compounds such as caffeic acid seemed far more active than caffeine itself.

Fossils from Queensland suggest a newly recognized marsupial order may have survived in Australia for around 35 million years, rewriting part of the story of how the continent's unique mammals evolved. The discovery challenges the idea that Australia's marsupials all came from a single straightforward ancestral lineage.

The asteroid that wiped out the dinosaurs was likely an exceptionally rare CO chondrite from a distant region of the solar system. Its unusual chemistry suggests that planet-cooling dust and debris, rather than sulfur inside the asteroid, may have delivered the deadliest blow.

A low-cost antidepressant may offer new hope for people struggling with long COVID fatigue. In a randomized clinical trial involving 399 adults, fluvoxamine significantly reduced fatigue and improved quality of life compared with a placebo, making it one of the first medications to show meaningful benefits for this disabling condition.

Several popular sugar substitutes may not be as harmless as they seem. Adults who consumed the most artificial sweeteners showed substantially faster declines in memory and thinking, especially if they were under 60 or had diabetes. The highest intake was linked to cognitive aging roughly 1.6 years faster than the lowest intake. Researchers stressed that more studies are needed before concluding that sweeteners are the cause.

A 12-week intermittent fasting program produced weight-loss benefits that were still visible a year later. Participants who ate within an eight-hour window maintained more weight loss than those who followed their usual longer eating schedule. Both early and late eating windows worked, while early fasting appeared especially helpful for preserving fat loss.

A study of 225 newborns suggests prenatal estrogen may have played a role in the evolution of larger human brains. Boys with finger-length patterns linked to higher estrogen exposure before birth tended to have larger head circumferences, which are strongly associated with brain size. The same connection was not seen in girls.

Seismic waves have revealed that the oceanic plate beneath the Ontong Java Plateau was dramatically transformed by the colossal volcanic activity that created it more than 100 million years ago. Researchers found a complex structure of horizontal layers cut through by vast swarms of vertical magma channels, along with unusually slow seismic waves suggesting that deep-rising magma chemically altered the plate itself.

The Mediterranean diet may influence aging through tiny proteins produced inside the cell’s mitochondria. Older adults who followed the diet most closely had higher levels of humanin and SHMOOSE, which have been linked to heart and brain protection. Olive oil, fish, legumes, and fewer refined carbohydrates appeared especially important. The findings could eventually help scientists develop more personalized nutrition plans for healthy aging.

JWST has captured unusually detailed images of gas feeding the supermassive black hole at the center of NGC 4696. A vast filament appears to funnel material into an 800-light-year-wide spinning disk, where gas races around at up to 600 kilometers per second. The findings suggest black holes may recycle their own fuel by heating gas with jets and later drawing the cooled material back in.

A catastrophic asteroid breakup may have triggered a huge wave of impacts across the inner solar system about 800 million years ago. The debris was launched from near a gravitational gateway controlled by Jupiter, sending fragments toward Earth, the Moon, and Mars. The bombardment may explain ancient lunar craters and could have contributed to major climate and biological changes on Earth.

A major DNA study has rewritten the koala's evolutionary story, revealing that the species suffered a dramatic population collapse about 100,000 years ago, long before humans arrived in Australia. By calculating the koala's mutation rate for the first time and analyzing hundreds of genomes, researchers discovered that every living koala traces back to a small group that survived extreme climate shifts and later repopulated eastern Australia.

A team of mathematicians used whimsical "silly sprinklers" to solve a physics mystery that has puzzled scientists for decades. Their experiments showed that the rotation of both normal and reverse sprinklers is driven by the momentum of flowing water, not by the outside water flow or other long-standing theories. The results finally provide a clear answer to Feynman’s famous sprinkler problem. They could also help engineers design more efficient fluid-powered machines.

Scientists say new technologies have reopened the debate over whether Mars could someday be terraformed, turning a once impossible idea into a serious research topic. Before anyone tries to reshape the Red Planet, though, researchers say we must understand the risks, including what might be lost if Mars already harbors its own forms of life.

Tiny plastic particles in drinking water may be doing more than contaminating the environment. New research suggests nanoplastics can actually help harmful bacteria survive by strengthening the slimy biofilms they form inside water systems. These tougher biofilms become more resistant to disinfectants, making them harder to remove and potentially increasing public health risks.

A new particle detector called PLATON could replace millions of tiny detector components with a single block of light-producing material. Using a light-field camera, highly sensitive photon sensors, and AI, it reconstructs particle paths in fast, detailed 3D. Simulations suggest it could match or surpass today’s best detectors while being far easier to scale. The technology may also lead to sharper PET medical scans.

A large laboratory study found that many commonly used sweeteners can directly change the growth of gut bacteria. Researchers identified more than 100 cases in which sweeteners behaved differently when combined with medications, caffeine, or flavorings. The combination of isosteviol and the antidepressant duloxetine was especially disruptive, reducing beneficial bacteria and overall microbial diversity.

Researchers have created self-destructing living plastic that uses engineered bacteria to completely break itself down when activated. The material degrades in just six days without creating microplastics, offering a potential new solution for single-use plastic waste.

A new experimental treatment may have found a way to outsmart glioblastoma’s toughest defense: the blood-brain barrier. Researchers used sugar-coated nanoparticles to ferry genetic instructions that restore a key tumor-suppressing protein directly into brain cancer cells. In mouse studies, the therapy increased median survival by 50% while shrinking tumors without noticeable damage to other organs.

A distant Sun-like star appears to have devoured one of its planets, leaving behind a surprising chemical fingerprint. Researchers found an unusually high concentration of lithium, a strong sign that planetary material was mixed into the star. Careful comparisons with dozens of similar stars confirmed the signal is highly unusual, and scientists think a massive brown dwarf companion may have helped send the planet on its fatal plunge.

Scientists have identified a hidden feedback loop that may explain how Earth has regulated its climate for tens of millions of years. As sea levels rose and fell, they changed how much phosphate reached the open ocean, affecting marine life and the amount of carbon buried beneath the seafloor. That burial removed carbon dioxide from the atmosphere, helping cool the planet.